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- Saturday Morning RPG
- Save Room
- Severed
- Shantae and the Pirate’s Curse
- Shantae and the Seven Sirens
- Shantae: Half Genie Hero
- Sherlock Holmes: Crimes & Punishments
- Sherlock Holmes: The Awakened (2023)
- Sherlock Holmes: The Devil’s Daughter
- She Sees Red
- Sinking City, The
- SNK Heroines: Tag Team Frenzy
- SNK 40th Anniversary Collection
- Solitaire Conspiracy, The
- Songs for a Hero
- Sonic Mania
- Space Invaders Invincible Collection
- Spelunker HD Deluxe
- Spirit Hunter: NG
- Spyro: Reignited Trilogy
- Stardew Valley
- Steins;Gate Elite
- Streets of Rage 4
- SuperEpic
- Super Meat Boy
- Super Robot Wars 30
