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- Samurai Shodown V
- Serious Sam 2
- Serious Sam: The First Encounter
- Serious Sam: The Second Encounter
- Shadow of Memories
- Shenmue II
- Shikigami no Shiro
- Shikigami no Shiro II
- Shrek SuperSlam
- Silent Hill 2
- Silent Hill 4: The Room
- Simpsons, The: Road Rage
- Smashing Drive
- Star Wars: Knights of the Old Republic
- Star Wars: Knights of the Old Republic II: The Sith Lords
- Sudeki
- Suffering, The
- Suffering, The: Ties That Bind
- Syberia
- Syberia II
